Hone your critical appraisal skills with NEJM Evidence

What is NEJM Evidence?

New England Journal of Medicine Evidence (NEJM Evidence) is an online journal which publishes original research and focuses on clinical trial design and decision-making. It often includes an editorial article to accompany the research article which analyses and appraises the trial design and discusses any problematic elements.
This offers you the opportunity to examine research articles and develop your own critical appraisal skills.
Learn more about NEJM Evidence, including a short video, from the NEJM website.

Example articles

Here are some example articles. Read the research then follow up with the discussion article.

• Original article: Wrist Splinting versus a Placebo Soft Bandage for Carpal Tunnel Syndrome DOI: https://doi.org/10.1056/EVIDoa2500261
• Editorial: Policy Implications of Placebo Bandage for Carpal Tunnel Syndrome DOI: https://doi.org/10.1056/EVIDe2600038

• Original article: Every Six-Month versus Single-Dose Adjuvant Zoledronate in Early Breast Cancer DOI: https://doi.org/10.1056/EVIDoa2500202
• Editorial: One and Done — Single-Dose Zoledronic Acid in Early-Stage Breast Cancer DOI: https://doi.org/10.1056/EVIDe2600083

• Original article: Outcomes of Pneumonia in ICUs in Low- and Middle-Income Countries — A Systematic Review DOI: https://doi.org/10.1056/EVIDoa2500244
• Editorial: Severe Pneumonia in Low- and Middle-Income Countries — A Gap We Can Close DOI: https://doi.org/10.1056/EVIDe2600111

• Original article: Solriamfetol for Excessive Sleepiness in Early-Morning Shift Work Disorder DOI: https://doi.org/10.1056/EVIDoa2500190
• Editorial: Bright and Early…Now Also Awake! DOI: https://doi.org/10.1056/EVIDe2500330

• Review article: Reading and Interpreting Quality-of-Life Results in Cancer Trials DOI: https://doi.org/10.1056/EVIDra2400340

Why read NEJM Evidence?

NEJM Evidence can provide useful articles for discussion in your:

• Journal clubs
• Department meetings
• Mentor discussions
• Skills development

Access NEJM Evidence

Both Keele University students and UHNM staff can access full-text of NEJM Evidence:

• Keele students – log in with your Keele email and password
• UHNM staff – log in with your NHS OpenAthens username and password

NHS staff can receive table of contents for the latest issue of NEJM evidence by signing up to our journal etocs on KnowledgeShare. Complete this online form.

More help

Contact the Health Library for help accessing resources and finding the information you need.